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PROstaTE Cancer Treatment and Obesity in Zoladex-Astrazeneca Treated Patients (PROTECT-Z)

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AstraZeneca

Status

Completed

Conditions

Obesity
Prostate Cancer

Study type

Observational

Funder types

Industry

Identifiers

NCT01020604
NIS-OHU-ZOL-2009/1

Details and patient eligibility

About

The reports on relationship of obesity and biochemical or clinical recurrence of prostate cancer are controversial. Several reports have shown that obesity is associated with increased risk of biochemical or clinical failure after radical prostatectomy. Other prospective studies have shown no adverse effect of obesity on long-term outcomes after prostatectomy. Limited reports are available on the impact of obesity on prostate cancer progression after radiotherapy. Primary: to assess percentage recurrence rate among normal weight and overweight or obese prostate cancer patients treated by adjuvant Zoladex therapy. Secondary: to determine the Quality of Life differences among normal and overweight or obese prostate cancer patients by a Quality of Life questionnaire

Enrollment

1,376 patients

Sex

Male

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Histologically proven prostate cancer patients being on adjuvant Zoladex treatment after primary therapy or on adjuvant therapy without primary curative therapy

Exclusion criteria

-Prostate cancer patients refractory to hormonal therapy, not agreeing to participate, allergy against treatment

Trial contacts and locations

34

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Data sourced from clinicaltrials.gov

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