Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients

Civil Hospices of Lyon

Status: Completed

Conditions: Prosthetic Joint Infection; Antibiotic Resistant Infection

Treatments: Other: Antibiotic pretreatment

Study type: Observational

Funder types: Other

Identifiers

NCT03848091

18-030

Details and patient eligibility

About

One-step exchange arthroplasty is more and more used in the treatment of chronic infections, especially in patients at risk anesthetic.

This strategy is not recommended in patients infected with multidrug-resistant organisms or difficult to treat because of a risk of bacterial persistence on the new implant.

Antibiotic pretreatment by a narrow-spectrum molecule and for which resistance acquisition is difficult might be of interest to try to reduce the inoculum and avoid contamination of the new implant.

Enrollment: 13 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients having had a antibiotic pretreatment targeted before a one step exchange arthroplasty

Exclusion criteria

• none

Trial design

13 participants in 1 patient group

Antibiotic pretreatment

Description:

patients having had an antibiotic pretreatment before a one-step exchange arthroplasty

Treatment:

Other: Antibiotic pretreatment