Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care. (OASIS²)

Assistance Publique - Hôpitaux de Paris

Status: Enrolling

Conditions: Osteoarticular Infections; Prosthetic Joint Infection; Intensive Care Patients

Treatments: Other: Global cohort

Study type: Observational

Funder types: Other

Identifiers

NCT07107685

APHP250872

Details and patient eligibility

About

This is an observational, retrospective, multicenter study based on the use of demographic, clinical and biological data from deceased patients admitted between 2018 and 2022 to critical care with a principal or associated diagnosis of joint prosthesis infection.

Data from this study will be combined with that from the OASIS study (APHP241174/ ID-RCB: 2024-A01769-38) concerning osteoarticular sepsis on prosthetic material in critical care of living patients.

The aim of this study is to improve our knowledge of the profile, care trajectories and outcomes of patients hospitalized in critical care in the context of osteoarticular material sepsis.

The results of the study could help identify at-risk populations and improve management strategies for patients with osteoarticular sepsis.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18 years or older.
• Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022, lasting at least 48 hours, with a prosthetic joint infection (hip, knee, or shoulder prosthesis infection) as the primary or associated diagnosis.
• Deceased patient who had not refused data processing.

Exclusion criteria

• Infection involving osteosynthesis material
• Infection involving spinal instrumentation
• Patient with multiple infected prostheses
• Recurrence of prosthetic infection with the same microorganism as a previous episode
• Patient under legal protection
• Pregnant or breastfeeding patient
• Patient deprived of liberty