Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery

University of Manchester

Status

Completed

Conditions

Wisdom Tooth

Postoperative Pain

Treatments

Drug: Bupivacaine

Drug: ibuprofen

Drug: Brufen retard

Study type

Interventional

Funder types

Other

Identifiers

NCT00895843

9938

Details and patient eligibility

About

The purpose of this study is to investigate whether robust analgesic regime (protective analgesia) can improve postoperative pain experience for patients undergoing lower wisdom teeth extraction under day case general anaesthetic.

Full description

The aim of the study was to demonstrate and improve postoperative pain experience using protective analgesia for patients undergoing oral surgery under day case general anaesthesia.

The primary objective was to investigate the efficiency of protective analgesia using combined effects of sustained release ibuprofen and bupivacaine nerve block in attenuation of postoperative pain following impacted third molar surgery under day case general anaesthesia.

The secondary objective was to document the safety and tolerability profile of conventional release versus sustained released ibuprofen with bupivacaine block in subjects undergoing impacted third molar surgery under day case general anaesthesia.

Enrollment

122 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

healthy male and female patients aged 18 years and over
patients requiring removal of one or more third molars, with at lease one completely or partially impacted in the mandible needing bone removal

Exclusion criteria