Protective Effect of Electroacupuncture on Lung in Patients Undergoing General Anesthesia

Lingling Ding

Status: Unknown

Conditions: Lung Injury, Ventilator Induced; Electroacupuncture

Treatments: Other: electroacupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT05019079

LDing

Details and patient eligibility

About

Objective to investigate the protective effect of preoperative electroacupuncture on lung function in patients with mechanical ventilation for more than 2 hours under general anesthesia

Full description

Randomized parallel control study. From September 1, 2021 to December 31, 2022, patients with mechanical ventilation time more than 2 hours will be randomly divided into electroacupuncture pretreatment group and blank control group. The blood gas index, ventilator parameters and serum inflammatory factor concentration of patients will be evaluated to evaluate whether electroacupuncture has protective effect on lung function of patients with mechanical ventilation.

Enrollment: 72 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing general anesthesia in our hospital;
• Ages 18-60;
• American Society of Anesthesiologists (ASA) grade ⅱ ~ III , no severe respiratory, circulation, liver, kidney, coagulation function abnormalities;
• Expected duration of operation >2h;
• Surgical grade 2-4;
• No serious lung infection and lung disease;
• Body mass index (BMI) 18~30 kg/m2; There are no contraindications for electroacupuncture stimulation.

Exclusion criteria

• Patients with severe circulatory or other system dysfunction;
• Patients with pulmonary and one-lung ventilation;
• Unwilling to cooperate with the patient;
• Patients with low compliance.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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72 participants in 2 patient groups

electroacupuncture group

Experimental group

Description:

In the electroacupuncture group, acupoints of Lieque (+), Chize (-), Sanyinjiao (-), Zusanli (+), Tanzhong (+) and Yutang (-) will be selected for electrical stimulation. Density wave will be selected, and the current intensity should be tolerated by the patients. Conventional anesthesia operation could be started after the connection of electroacupuncture, and acupuncture point stimulation was stopped 30min later.

Treatment:

Other: electroacupuncture

control group

No Intervention group

Description:

The patient underwent routine anesthesia without acupuncture treatment