Protein and Satiety in Older Adults (PROSAT)

University of Reading

Status: Completed

Conditions: Energy Intake; Gastric Emptying; Appetitive Behavior; Physical Activity

Treatments: Other: High Protein Milkshake; Other: Normal Milkshake

Study type: Interventional

Funder types: Other

Identifiers

NCT05507801

UREC 21/40

Details and patient eligibility

About

This study aims to assess the effect of protein on appetite, food intake and gastric emptying in older adults (≥ 65 years) that are more and less active.

Full description

To investigate the differences in food intake in older adults that are more or less active and assess any differential responses to protein intake.

To compare the effect of meals with high or low protein level but equal in energy and volume on appetite and gastric emptying in older adults that are more or less active (≥ 65 years).

Enrollment: 38 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy
• aged ≥ 65 years

Exclusion criteria

• having diabetes or disability or any disease that are likely to influence physical activity or appetite.
• having an allergy to any of the test foods;
• disliking or cannot eat any of the test foods;
• being obese (BMI > 30 kg/m2);
• taking medications known to influence appetite, food intake or body weight in the past three months;
• being on a weight loss diet;
• smoking more than 10 cigarettes a day;
• not meeting the cut-off point criteria based on the accelerometer data (108.25 ≤ min/per day of moderate and vigorous activity for women or 162 ≥ min/per day moderate and vigorous activity for women and 100.1 ≤ min/per day of moderate and vigorous activity for men or 133.25 ≥ min/per day moderate and vigorous activity for men).

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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38 participants in 2 patient groups

High Physically Active Group

Experimental group

Description:

Based on accelerometer data, women with 162 ≥ min/per day moderate and vigorous activity or men 133.25 ≥ min/per day moderate and vigorous activity.

Treatment:

Other: Normal Milkshake

Other: High Protein Milkshake

Low Physically Active Group

Experimental group

Description:

Based on accelerometer data, women with 108.25 ≤ min/per day moderate and vigorous activity or men 100.1 ≤ min/per day moderate and vigorous activity.

Treatment:

Other: Normal Milkshake

Other: High Protein Milkshake