Protein Hydrolyzation and Glycemic Control

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Diabetes

Treatments: Dietary Supplement: Protein hydrolyzation

Study type: Interventional

Funder types: Other

Identifiers

NCT01034618

06-3-081

Details and patient eligibility

About

The insulinotropic effects of protein hydrolysate/amino acid ingestion have been shown to regulate blood glucose homeostasis in both type 2 diabetes patients and normoglycemic controls. The objective of the study is to investigate the optimal dose of such an insulinotropic mixture.

Sex: Male

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male
• Age between 40 and 70 years
• Oral blood glucose lowering medication
• BMI < 35 kg/m2

Exclusion criteria

• Exogenous insulin use
• Cardiac disease (any cardiac event in the last 5 years)
• Diabetic complications (microvascular complications, microalbuminuria: albumin:creatinine ratio >2,5)

Trial design

0 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Protein hydrolyzation

Intact protein

Experimental group

Treatment:

Dietary Supplement: Protein hydrolyzation

Protein hydrolysate

Experimental group

Treatment:

Dietary Supplement: Protein hydrolyzation