Protein Intake Distribution to Support Muscle Anabolism in Healthy Young Adults

Maastricht University Medical Centre (MUMC)

Status: Not yet enrolling

Conditions: No Condition, Healthy Individuals

Treatments: Dietary Supplement: Protein intake; Dietary Supplement: protein intake

Study type: Interventional

Funder types: Other

Identifiers

NCT07245199

NL-010056 / METC25-038 (Other Identifier)

Details and patient eligibility

About

The purpose of the study is to evaluate whether the distribution pattern of daily protein intake affects how much muscle protein can be built in the muscle after resistance exercise and at rest.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged between 18-40 years
• Healthy
• 18.5 ≤ BMI 30 ≤ kg・m-2

Exclusion criteria

• Smoking
• Sports/exercise >4 sessions/week or a structured resistance or endurance training schedule
• Lactose intolerant or allergies to milk protein
• A history of neuromuscular problems
• Use of anticoagulation medication
• Individuals on any medications known to affect protein metabolism (i.e. , non-steroidal anti-inflammatories, or prescription acne medications).
• Strict vegetarian
• Injury or condition that would limit the participant from performing the resistance exercise.
• Pregnancy
• Hormone replacement therapy
• Blood donation within the past 2 months

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 3 patient groups

BALANCED

Experimental group

Treatment:

Dietary Supplement: protein intake

Dietary Supplement: protein intake

SIP

Experimental group

Treatment:

Dietary Supplement: Protein intake

BOLUS

Experimental group

Treatment:

Dietary Supplement: protein intake

Dietary Supplement: protein intake