Protein Requirements in Endurance-trained Athlete (EP)

University of Toronto

Status and phase

Completed

Early Phase 1

Conditions

Healthy

Increased Metabolic Requirement

Treatments

Dietary Supplement: amino acids intake

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT02478801

IAAO-E

Details and patient eligibility

About

Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).

Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.

Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than RDA based on nitrogen balance data.

Therefore, the purpose of this study is to measure the protein requirement in endurance trained adults using the IAAO technique.

Enrollment

9 patients

Sex

Male

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy, male, endurance-trained participants who regularly more than 40 km/week
Ability to perform the exercise stimulus (20 km run) on metabolic trial.

Exclusion criteria

Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
Regular tobacco use
Illicit drug use