Proteome Remodelling

Morten Hostrup, PhD

Status: Completed

Conditions: Skeletal Muscle Physiology

Treatments: Other: Endurance training; Other: Resistance training; Other: Sprint training

Study type: Interventional

Funder types: Other

Identifiers

NCT04136457

MiDy

Details and patient eligibility

About

The purpose of the project is to investigate the proteome signature dynamics and remodelling in human skeletal muscle induced by exercise training

Enrollment: 72 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men and women
• VO2max > 55 mL/min/kgLM for men and > 50 for women (only applicable for endurance and sprint training interventions)
• BMI < 26

Exclusion criteria

• Chronic disease deemed by the medical doctor to pose a risk or to affect study outcomes
• smoking
• Use of prescription medicine deemed by the medical to affect study outcomes
• Pregnancy

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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72 participants in 3 patient groups

Endurance

Experimental group

Description:

Endurance training

Treatment:

Other: Endurance training

Resistance

Experimental group

Description:

Resistance training

Treatment:

Other: Resistance training

Sprint

Experimental group

Description:

Sprint training

Treatment:

Other: Sprint training