Proteomic Analysis of Human Hepatocellular Carcinoma

Far Eastern Memorial Hospital

Status: Completed

Conditions: Carcinoma, Hepatocellular

Treatments: Procedure: Operation

Study type: Interventional

Funder types: Other

Identifiers

NCT01177631

97068

Details and patient eligibility

About

This is a pilot study to evaluate the difference between the protein expression between hepatocellular carcinoma and tumor with vessel invasion in Asian patients with hepatocellular carcinoma.

Enrollment: 5 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Arm A: Hepatocellular carcinoma with vessel invasion:

• hepatocellular carcionoma, pathologic diagnosed.
• image documented vessel invasion, including portal vein thrombosis
• eligible for surgical intervension.

Arm B: hepatocellular carcinoma without vessel invasion:

• hepatocellular carcinoma, pathologic diagnosed or clinical diagnosed according to EASL criteria.
• no vessel invasion on image.

Arm C: Healthy hepatitis carrier:

• patients age >18 years old with hepatitis B or C
• normal liver function.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)