Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer

Carol Fabian, MD

Status: Withdrawn

Conditions: Breast Cancer

Treatments: Procedure: Fine needle aspiration

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00329017

9814

Details and patient eligibility

About

A study to examine the potential associations between common single nucleotide polymorphisms and pre-cancerous conditions in breast tissue specimens from postmenopausal women.

Full description

A study to examine the correlation between single nucleotide polymorphisms (SNPs) affecting steroid and carcinogen metabolism and benign breast tissue cytomorphology collected via random periareolar fine needle aspiration in postmenopausal women at increased risk for breast cancer and taking hormone replacement therapy.

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• postmenopausal women on or off hormone replacement therapy
• at high risk of developing breast cancer determined by family or personal history
• postmenopausal women not on hormone replacement therapy for at minimum six months prior to corresponding aspiration
• willing to participate in companion protocol (KUMC HSC#4601) for random periareolar fine needle aspiration (RPFNA) for correlational studies

Exclusion criteria

• women who have been on raloxifene, tamoxifen, letrozole, anastrozole or exemestane within the six months prior to RPFNA.

Trial design

0 participants in 1 patient group

1

Description:

Post-menopausal women who are at increased risk for development of breast cancer on the basis of family or personal history.

Treatment:

Procedure: Fine needle aspiration