Protocol Optimization in CT for the Quantification of BMD

Hatem Alkadhi

Status

Completed

Conditions

Osteoporosis, Osteopenia

Bone Loss

Treatments

Diagnostic Test: Bone Mineral Density quantification

Study type

Interventional

Funder types

Other

Identifiers

NCT06305156

CT_BMD_1

Details and patient eligibility

About

Bone mineral density is an important measurement to detect osteoporosis.

The goal of this clinical trial is to compare bone mineral density measurements in CT examinations and DXA scans. The main question it aims to answer is:

How good is the measurement of bone mineral density in the new photon-counting CT in comparison to DXA
How can we optimize the CT scan for bone mineral density

Participants will undergo:

Clinically indicated CT scan on day of inclusion
Study related DXA scan on a separate appointment

Enrollment

167 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Informed Consent signed by the subject
Referral to a regular clinically indicated CT examination covering the lumbar area (e.g., Abdomen, Thorax + Abdomen, Neck + Thorax +Abdomen)
Informed written and oral consent (interpreter present in case of foreign language patients)
No contraindication to the clinically indicated CT examination

Exclusion criteria

Patients < 18 years
Pregnant women
Vulnerable subjects
Contraindications to the clinically indicated CT scan
Multiple Myeloma
Diffuse bone metastasis
Fixateur interne in the lumbar spine
Kyphoplasty in the lumbar spine
Enterally administrated contrast agent
Obtaining informed consent is not possible
Withdrawal of consent orally or in writing
Inability to follow the procedures of the investigation, e.g., due to language problems, psychological disorders, dementia, etc. of the subject
Immobility (patients confined to a wheelchair or to bed)