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Psychoeducational Programme for PD Patients With STN-DBS (PSYCHE)

G

Groupe Hospitalier Pitie-Salpetriere

Status

Completed

Conditions

Parkinson's Disease

Treatments

Behavioral: Psychoeducational programme

Study type

Interventional

Funder types

Other

Identifiers

NCT02554370
2006-A00230-51

Details and patient eligibility

About

Bilateral subthalamic deep-brain stimulation is a well-established therapeutic option to improve motor signs and reduce dopaminergic treatment and related motor complications in patients with severe forms of Parkinson's disease (PD). However, psychological disorders and socio-familial maladjustment are less clearly improved with subthalamic stimulation with an aggravation of the social adjustment described in about 1/3 of cases, with work disruption, divorce or familial conflict. The caregivers have also been reported to present negative well-being after surgery with an aggravation of the quality of life. In the present study, the investigators evaluate the effects of a perioperative psychoeducational programme to avoid postoperative socio-familial maladjustment in PD patients candidate for subthalamic stimulation, and their caregivers, in a randomized controlled study.

Full description

After inclusion, patients (and their caregivers) are randomized into two groups stratified on their preoperative social adjustment scale couple domain score : usual treatment and psychoeducational programme or usual treatment alone (Figure). The psychoeducational programme focuses on 3 domains: 1) neurosurgical procedure and neurological outcome, 2) social life including work, social and familial relationship, 3) couple relationship. The programme consists of 7 sessions with 3 to 4 couples at the same session, except for the 'couple relationship' domain. Each domain is tackled in a two-way manner with information/education proved by the investigator and discussion of the patients' and caregivers' expectations during one session. The following session started with a 'Questions and Answers' on the previous domain and then information on another domain. Four sessions were carried out prior to surgery and 3 after.

Enrollment

19 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Parkison's disease
  • Patients candidate for STN DBS
  • Caregiver agreeing to participate
  • Signed informed consent

Exclusion criteria

  • Contra-indication to STN-DBS
  • No caregiver agreeing to participate
  • Dementia
  • Severe ongoing psychiatric disorder

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

19 participants in 2 patient groups

Psychoeducational programme
Experimental group
Description:
Psychoeducational programme
Treatment:
Behavioral: Psychoeducational programme
Usual care
No Intervention group
Description:
No psychoeducational programme

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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