Psychological Evaluation According Colonic Colonization by Escherichia Coli of Patients After Colorectal Surgery (MicrobioPSY)

University Hospital, Clermont-Ferrand

Status: Completed

Conditions: Colorectal Cancer

Treatments: Other: Psychiatric evaluation

Study type: Interventional

Funder types: Other

Identifiers

NCT02970513

2016-A01233-48 (Other Identifier)

CHU-0288

Details and patient eligibility

About

The purpose of this study is to determine whether the presence of pathogenic Escherichia coli in colon is associated with psychiatric disorders.

Full description

Colonic colonization by pathogenic Escherichia coli was determined when patients were operated on for colorectal cancer.

Several years later, the investigator investigate past and actual psychiatric disorder using the Mini International Neuropsychiatric Interview (MINI). Actual depression and anxiety scores are evaluated with Hamilton scales and personality traits are investigated using Personality Inventory for DSM-5 (PID-5).

Anxiety and depression scores, psychiatric diagnoses (MINI) and personality traits were compared in patients according to Escherichia coli presence/absence.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients operated on for colorectal cancer in the digestive surgery department of Clermont-Ferrand hospital
• patients older than 18 years,
• patients whose Escherichia coli colonization was analyzed after surgery
• patients which are always followed by the digestive surgery department.

Exclusion criteria

• Patients with dementia will not be included, according to the MMSE score:
• 22 if no grade
• 23 if study certificate or CAP or college without patent
• 25 if patent or school without the tray
• 26 or more when bin

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

patients operated on for colorectal cancer

Experimental group

Treatment:

Other: Psychiatric evaluation