Psychological Support Interventions for Women With Endometriosis (ENDOPSY)

Civil Hospices of Lyon

Status: Not yet enrolling

Conditions: Endometriosis

Treatments: Behavioral: Mixed Psychotherapy; Behavioral: Individual Psychotherapy; Behavioral: Socio-Aesthetic Group Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT07280052

2025-A02054-45 (Other Identifier)

69HCL25_0655

Details and patient eligibility

About

Endometriosis is associated with severe pain, impaired quality of life and significant psychological distress. Psychological support may help improve emotional regulation, mental health, and quality of life in affected women. This randomized controlled trial evaluates the impact of three psychological support interventions-individual psychotherapy, socio-aesthetic group therapy, and a mixed approach combining both-on psychological symptoms and quality of life. Forty participants will be randomized into four parallel arms. The study hypothesis is that psychological support interventions improve psychological functioning and disease-related quality of life compared with no intervention, and that the combined mixed approach may produce greater benefits than the individual or group interventions alone.

Enrollment: 40 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult women ≥18 years
• Clinical diagnosis of endometriosis
• Ability to understand and complete psychological evaluations
• Signed written informed consent

Exclusion criteria

• Ongoing psychotherapy
• Cognitive, sensory or language impairments preventing participation
• Participation in another interventional clinical study
• Persons under legal protection
• Non-French speakers
• Pregnancy or breastfeeding

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 4 patient groups

CONTROL Group - No Psychological Intervention

No Intervention group

Description:

Participants receive no structured psychological intervention during the 5-month study period. Usual medical care continues without modification.

INDIVIDUAL PSYCHOTHERAPY - Individual Psychotherapy (PI)

Other group

Description:

Individual psychotherapy sessions conducted by trained clinical psychologists. Ten sessions lasting 45 minutes each are delivered every two weeks over a 5-month period. The intervention focuses on emotional experience, psychological support, and associative processes related to endometriosis.

Treatment:

Behavioral: Individual Psychotherapy

SOCIO-AESTHETIC GROUP THERAPY - Socio-Aesthetic Group Therapy (PG)

Other group

Description:

Six socio-aesthetic group therapy workshops delivered every two weeks over approximately three months. Sessions last 2 hours each and include skincare, sensory exploration, self-image work, and shared emotional expression. Co-conducted by a socio-esthetician and a psychologist.

Treatment:

Behavioral: Mixed Psychotherapy

MIXED PSYCHOTHERAPY - Mixed Individual + Group Psychotherapy (PGI)

Other group

Description:

Combined intervention including two initial individual sessions, alternating individual and group therapy thereafter, and three closing individual sessions. Duration and number of sessions match the individual and group-only interventions.

Treatment:

Behavioral: Socio-Aesthetic Group Therapy