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Psychological Treatment of Overweight Binge Eaters

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The Washington University

Status and phase

Completed
Phase 2
Phase 1

Conditions

Obesity/Epidemiology
Obesity/Therapy
Cognitive Therapy/Methods
Mental Disorders/Epidemiology
Binge Eating Disorder

Treatments

Behavioral: Cognitive Behavioral Therapy (CBT)
Behavioral: Interpersonal Therapy (IPT)

Study type

Interventional

Funder types

Other

Identifiers

NCT01208272
R29MH051384

Details and patient eligibility

About

Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED.

Full description

Cognitive-behavioral therapy (CBT) has documented efficacy for the treatment of binge eating disorder (BED). Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-term impact and time course on other BED-related symptoms remain largely unknown. This study compares the effects of group CBT and group IPT across BED-related symptoms among overweight individuals with BED. METHODS: One hundred sixty-two overweight patients meeting DSM-IV criteria for BED were randomly assigned to 20 weekly sessions of either group CBT or group IPT. Assessments of binge eating and associated eating disorder psychopathology, general psychological functioning, and weight occurred before treatment, at posttreatment, and at 4-month intervals up to 12 months following treatment. RESULTS: Binge-eating recovery rates were equivalent for CBT and IPT at posttreatment (64 [79%] of 81 vs 59 [73%] of 81) and at 1-year follow-up (48 [59%] of 81 vs 50 [62%] of 81). Binge eating increased slightly through follow-up but remained significantly below pretreatment levels. Across treatments, patients had similar significant reductions in associated eating disorders and psychiatric symptoms and maintenance of gains through follow-up. Dietary restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups. Patients' relative weight decreased significantly but only slightly, with the greatest reduction among patients sustaining recovery from binge eating from posttreatment to 1-year follow-up. CONCLUSIONS: Group IPT is a viable alternative to group CBT for the treatment of overweight patients with BED. Although lacking a nonspecific control condition limits conclusions about treatment specificity, both treatments showed initial and long-term efficacy for the core and related symptoms of BED.

Enrollment

162 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • DSM-IV research criteria for binge-eating disorder
  • Average of greater than or equal to 2 days of binge eating per week for at least 6 months' duration
  • Marked stress regarding binge eating
  • At least 3 to 5 associated behavioral features (e.g. eating when not physically hungry) Other study criteria
  • 18-65 years old
  • Body mass index, 27-48 kg/m squared

Exclusion criteria

  • Pregnant or planning to become pregnant
  • Taking weight-affecting or psychotropic medications
  • Psychiatric conditions warranting immediate treatment
  • Current enrollment in psychotherapy or a weight loss program

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

162 participants in 1 patient group

Binge Eating Disorder/Therapy
Experimental group
Treatment:
Behavioral: Interpersonal Therapy (IPT)
Behavioral: Cognitive Behavioral Therapy (CBT)

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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