Psychophysiological Effects of Music

Zhejiang University

Status: Completed

Conditions: Sadness

Treatments: Behavioral: Music

Study type: Interventional

Funder types: Other

Identifiers

NCT06516666

Music study in China

Details and patient eligibility

About

This study employed a repeated measure between-subjects design. Two groups (i.e., depressed group and non-depressed group) of participants were recruited. Each participant experienced four stages: baseline, neutral control, sadness induction, and music intervention. The outcome variables were self-reported emotion and Heart Rate Variability features. Emotions were reported at the end of every stage. Electrocardiogram signals were recorded throughout the experiment.

Enrollment: 149 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged 18-30 years
• Right-handed
• No recent illness or medication use
• No history of neurological or psychiatric disorders
• Normal or corrected-to-normal visual acuity (myopic participants wore glasses)
• Normal hearing

Exclusion criteria

• Incapable of giving written informed consent to this study
• Acute high suicide risk at baseline assessment
• Psychosis

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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149 participants in 2 patient groups

Depressed group

Experimental group

Description:

The participants were categorized into two groups using the Patient Health Questionnaire (PHQ-9) and the 17-item Hamilton Depression Rating Scale (HAM-D). PHQ-9 is a self-report scale. PHQ-9 scores of 5 or higher represent mild and severe depression, while PHQ-9 scores of lower than 5 mean normal condition. HAM-D is a scale administered by a healthcare professional. The cut-off point of the HAM-D scale is 8, which divides normal conditions from depressive conditions. The participants first completed PHQ-9. For those with PHQ-9 scores of 5 or higher, the trained researchers interviewed them and rated their severity of depression on the HAM-D. The participants first completed PHQ-9. For those with PHQ-9 scores ≥ 5, the trained researchers interviewed them and rated their severity of depression on the HAM-D. Those with HAM-D scores \> 8 were classified into the depressed group.

Treatment:

Behavioral: Music

Non-depressed group

Experimental group

Description:

Those with PHQ-9 scores \< 5 or HAM-D scores ≤ 8 were classified into the non-depressed group.

Treatment:

Behavioral: Music