Psychosocial and Behavioral Intervention for Stem Cell Transplant Patients and Their Family Caregivers

University of Pittsburgh

Status: Enrolling

Conditions: Stem Cell Transplant; Hematopoetic Stem Cell Transplantation; Hematopoetic Stem Cell Transplant

Treatments: Behavioral: Dyadic Problem Solving Training; Behavioral: Supportive Care

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT07107165

R01CA268004 (U.S. NIH Grant/Contract)

STUDY25020163

Details and patient eligibility

About

Adherence to the medical regimen after stem cell transplant is challenging for both patients and their family caregivers. The investigators propose a randomized clinical trial testing two brief psychosocial interventions to determine if either improves patient and family caregiver psychosocial and health-related outcomes.

Full description

The investigators propose a randomized controlled trial testing two brief, 4 session psychosocial interventions to help patients and family caregivers better manage the time period after hospital discharge from stem cell transplant. Patients and family caregivers will be randomized to either the skill learning intervention (n=52 patient-family caregiver dyads) or to the supportive care intervention (n=52 patient-family caregiver dyads). The intervention will be conducted via live video conferencing. Patients and family caregivers will complete questionnaires before the intervention and at 1-, 5-, 12-, 24 weeks afterwards. The investigators will determine whether the skills learning group has improved outcomes, including adherence to the medical regimen and perceived task efficacy.

Enrollment: 208 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient scheduled for stem cell transplant at the University of Pittsburgh Hillman Cancer Center
• 18 years or older
• having a family caregiver age 18 years or older also willing to participate in the study
• willing to accept randomization

Exclusion criteria

• Prior history of stem cell transplant
• Non-English speaking

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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208 participants in 2 patient groups

Dyadic Problem Solving Training (DPST)

Experimental group

Description:

DPST will teach problem solving skills to both the patient and family caregiver as they manage the medical regimen.

Treatment:

Behavioral: Dyadic Problem Solving Training

Supportive Care

Active Comparator group

Description:

Supportive Care will provide support to both the patient and family caregiver as they manage the medical regimen.

Treatment:

Behavioral: Supportive Care