PUFAs in Preterm Infants (PIPI)

Jilin University

Status: Not yet enrolling

Conditions: Intraventricular Hemorrhage; Necrotizing Enterocolitis; BPD - Bronchopulmonary Dysplasia; Periventricular Leukomalacia; Patent Ductus Arteriosus; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT06045130

2023-HS-050

Details and patient eligibility

About

The research endeavors to examine the critical composition of Polyunsaturated Fatty Acids (PUFAs) in premature infants across different gestational stages and under varying disease conditions, and delineate the metabolic attributes of PUFAs in premature infants and their interplay with the onset of diseases. This study anticipates furnishing a theoretical foundation for the rationalization of PUFAs supplementation in premature infants and for informing strategies related to disease prevention and management.

Enrollment: 600 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Infants born between 24 and 36 weeks of gestational age who are admitted within 24 hours of birth, including both premature and full-term newborns.

Exclusion criteria

Infants with severe congenital developmental abnormalities, those requiring external supplementation of PUFAs in addition to standard intravenous nutrition and breastfeeding, and those with a severe prognosis indicating non-survival during their hospitalization.