Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults (PEPICov)

Istanbul Arel University

Status: Completed

Conditions: Post COVID-19

Treatments: Other: Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults

Study type: Interventional

Funder types: Other

Identifiers

NCT05282043

PEPICov

Details and patient eligibility

About

When the literature search is conducted, it is seen that there are many studies examining the effects of COVID-19 disease on individuals in various disease groups (MS, stroke, Parkinson, COPD, asthma, etc.) and age groups (adult, geriatric, etc.). However, it has been determined that there is no study examining the impacts of this disease on functional capacity, physical activity, pulmonary function, emotional state, sleep, and quality of life in healthy young adults. This study will reveal whether COVID-19 disease causes an effect on the mentioned parameters in young adults. The aim of recent study is to investigate functional capacity, respiration, pain, depression, sleep and quality of life in young adults post COVID-19. For this purpose, participants' upper extremity and lower extremity muscle strength, 6-minute walking distance, O2 saturation, posture evaluation, spirometric evaluation, pain threshold, pain intensity, dyspnea, and leg fatigue measurements will be recorded. In addition to these measurements, general fatigue, quality of life, depression, physical activity level, sleep quality parameters will be evaluated and the data obtained will be analyzed with appropriate statistical methods.

The goals of recent work,

• To determine whether COVID-19 disease causes a decrease in functional capacity and changes in respiratory parameters in young adults, as well as to determine whether there are effects such as pain, depression, decreased sleep and quality of life,
• To determine whether there are significant changes in the values of the relevant outcome measurements in all the mentioned parameters,
• As a result of these, to determine the effects of COVID-19 disease on these parameters in young adults with objective, measurable data and to guide researchers and clinicians who do/will conduct studies on the subject.

Enrollment: 68 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• volunteers who are aged between 18-45 years
• cases, who were infected with COVID-19 and had at least 12 weeks after diagnosis
• cases, who have no symptoms of COVID-19 such as fever, cough, ageusia, anosmia, diarrhea, arthralgia, myalgia, sore throat, headache, chest pain

Exclusion criteria

• those have any cardiac or pulmonary disease history
• those have diagnoses of any psychological disease (major depression, anxiety disorder, etc.)
• those have any neurological or orthopaedic disease which hinders participation in physical activity

Trial design

Primary purpose: Screening

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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68 participants in 2 patient groups

post COVID-19 group

Experimental group

Description:

In this group cases, who were infected with COVID-19 and had at least 12 weeks after diagnosis, will be allocated. Those should have no symptoms of COVID-19 such as fever, cough, ageusia, anosmia, diarrhea, arthralgia, myalgia, sore throat, headache, chest pain.

Treatment:

Other: Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults

healthy control group

Active Comparator group

Description:

In this group cases, who were not infected with COVID-19 will be allocated.

Treatment:

Other: Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults