Pulmonary Arterial Hypertension in Systemic Sclerosis

IRCCS Policlinico S. Matteo

Status: Unknown

Conditions: Systemic Sclerosis; Pulmonary Arterial Hypertension

Study type: Observational

Funder types: Other

Identifiers

NCT00617487

EchostressSSc

Details and patient eligibility

About

The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with systemic sclerosis according to LeRoy criteria

Exclusion criteria

• Pregnancy
• Significant valvular disease
• Low left ventricular function upon echocardiography (ejection fraction<55%)
• History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.