Pulmonary Embolism and Stroke in Patient With Patent Foramen Ovale (EPIC-FOP)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Pulmonary Embolism; Recent Stroke; Patent Foramen Ovale

Study type: Observational

Funder types: Other

Identifiers

NCT01216423

EPIC-FOP

Details and patient eligibility

About

The cause of ischemic stroke remains frequently unknown. In patients with patent foramen ovale (PFO), the link between PFO and Stroke is unclear. The investigators hypothesize that the main mechanism is paradoxical embolism and decided to look for clinically apparent and silent cerebral embolism in patients with a recent pulmonary embolism.

Full description

Inclusion criteria :

• age > 18 years old
• confirmed pulmonary embolism
• informed consent
• social ensured

Exclusion criteria :

• pregnancy
• age < 18 years old
• protected major person (in sense of public health)
• consent refused
• MRI contraindications

Enrollment: 374 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age > 18 years old
• confirmed pulmonary embolism
• informed consent
• social ensured

Exclusion criteria

• pregnancy
• age < 18 years old
• protected major person (in sense of public health)
• consent refused
• MRI contraindications

Trial design

374 participants in 2 patient groups

Incidence of recent stroke in patients with PFO

Incidence of recent stroke in patients without PFO