Pulmonary Function in Non-hospitalized Adults and Children After Mild COVID-19

University of Rostock

Status: Completed

Conditions: SARS-CoV-2 Infection

Treatments: Diagnostic Test: lung function testing

Study type: Observational

Funder types: Other

Identifiers

NCT06318208

C-LCI

Details and patient eligibility

About

The study investigates whether patients with mild SARS-CoV-2 infection, who stayed at home during their infection and weren't hospitalized, have any persisting sequelae in pulmonary function.

Therefore, 110 patients, aged 6-60 years, were recruited by telephone 4-12 weeks after laboratory-confirmed positive PCR and invited for a lung function testing. Every patient with abnormalities in pulmonary function was invited to a follow-up 3 months after the first appointment to assess changes in lung function values.

Patients with a pre-existing lung disease and smokers within the last five years were excluded beforehand.

Additionally to lung function testing we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the pulmonary function testing.

Full description

110 patients, 90 adults and 20 children, were recruited. The lung function included LCI, FEV1, FVC and DLCO (Hb corrected). Additionally we did a throat swab at each appointment to analyse via Multiplex PCR whether the patients had any other respiratory infection at the time of the test.

Enrollment: 110 patients

Sex: All

Ages: 6 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• SARS-CoV-2 Infection, non-hospitalized during infection

Exclusion criteria

• Smoking, existing lung disease (COPD, Asthma bronchiale)