Pulmonary Impacts of Anaesthetic Modalities Evaluated by Ultrasound (PULCHO-KNEE)

Toulouse University Hospital

Status: Unknown

Conditions: Anesthesia

Treatments: Diagnostic Test: pleuropulmonary ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT03978169

RC31/18/0379

Details and patient eligibility

About

A prospective, observational, monocentric study aimed at identifying ultrasound changes in anaesthesia on the pulmonary parenchyma after knee arthroplastic surgery using the LUS score in the preoperative, immediate post-operative (D0) and late post-operative (D1) periods.

Full description

Post-operative pulmonary complications are responsible from morbidity and mortality close to cardiovascular complications.

Perioperative and post-operative respiratory changes are secondary to anaesthesia (general anaesthesia, elongated position, tidal volume) and to surgery in particular abdominal and cardiothoracic surgery.

Several risk factors related to patients were identified: age, ASA score> 2, functional dependence, chronic obstructive pulmonary disease, congestive heart failure, obesity, smoking.

Pulmonary ultrasound is a simple and rapid means of monitoring, widely used in resuscitation and developing in anaesthesia.

The hypothesis of the study is that anaesthesia and / or ventilation is responsible for lung lesions observable by ultrasound from the recovery room, even after extra-thoracic surgeries.

To do this, it will perform 3 pleuro-pulmonary ultrasound scans, preoperatively on the day of surgery, post-operatively in the recovery room and the day after surgery. LUS score will be calculated. Preoperative data (morphology, comorbidities), preoperative (ventilation, filling, position, type of anaesthesia - general anaesthesia with intubation or laryngeal mask, spinal anaesthesia- , type of surgery) and postoperative data (constants, oxygen therapy, complications) will be collected.

Enrollment: 99 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient undergoing scheduled primary knee arthroplasty :

• Partial knee replacement surgery

• Total knee replacement surgery

  • Type of Anaesthesia

• General anaesthesia with orotracheal intubation

• General anaesthesia with laryngeal mask

• Spinal anaesthesia

  • Major Patient
  • Oral non opposition collected after oral information of the study

Exclusion criteria

• Refusal to participate
• Preoperative pleural pathology (pleural effusion, pleural symphysis)
• Pregnancy
• Patient under authorship or curators
• non-affiliation to a social security scheme

Trial design

99 participants in 3 patient groups

General anaesthesia with orotracheal intubation

Description:

surgery patients under general anaesthesia with orotracheal intubation

Treatment:

Diagnostic Test: pleuropulmonary ultrasound

General anaesthesia with laryngeal mask

Description:

surgery patient under general anaesthesia with laryngeal mask

Treatment:

Diagnostic Test: pleuropulmonary ultrasound

Spinal anaesthesia

Description:

surgery's patients under Spinal anaesthesia

Treatment:

Diagnostic Test: pleuropulmonary ultrasound