Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery

China Medical University

Status and phase: Suspended; Phase 2; Phase 1

Conditions: Reperfusion Injury

Treatments: Device: electroacupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT02850471

pulmonary protection

Details and patient eligibility

About

TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary complications in patients who are receiving mechanical ventilation during general anesthesia for gynecologic laparoscopic surgery.

Full description

Participants: 100 patients who underwent elective gynecologic laparoscopic surgery Methods: We recruited 100 patients who are planned for gynecologic laparoscopic surgery. Patients were enrolled from March 1, 2015. We randomly allocated patients into two groups: controlled group ( patients treated without transcutaneous electrical acupoint stimulation) and TEAS group (patients treated with TEAS on Feishu, Hegu, Chize half an hour before the surgery). Blood pH, Pco2, Po2 and oxygen saturation were measured by an automatic blood gas analyzer immediately after obtaining the samples from the aorta. Sample all the patients blood before and after the surgery. And then measure the level of TNF-α, IL-1β, and IL-6.

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged from 65 to 75
• The American Society of anesthesiologists (American Society of Anesthesiology, ASA) class Ⅱ ~ III
• scheduled for gynecologic laparoscopic surgery under general anesthesia

Exclusion criteria

• pre-existing lung or caridac disease
• impaired kidney or liver function
• history of bronchial asthma or chronic obstructive pulmonary disease
• history of smoking
• respiratory infection in the previous 2 weeks
• preoperative use of bronchodilator, or a steroid

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

100 participants in 2 patient groups

TEAS group

Experimental group

Description:

Before anesthesia, patients in this group treated with Transcutaneous Electric Acupoint Stimulation (TEAS) which is an electroacupuncture on Feishu, Hegu, Chize half an hour before the surgery, using the device Hua Tuo SDZ-II Acupoint Stimulator. The stimulus parameters set as 2/100Hz, 2V, 30min.

Treatment:

Device: electroacupuncture

controlled group

No Intervention group

Description:

Patients in controlled group treated without TEAS or other placebo.