Pulmonary Rehabilitation in COPD: Effects of Two Aerobic Exercise Intensity in Patient-centered Outcomes

New University of Lisbon

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Other: Aerobic exercise training intensity

Study type: Interventional

Funder types: Other

Identifiers

NCT01944072

NOVA-FCM-MSAR-001

Details and patient eligibility

About

Trial design: An equivalence/non-inferiority randomized controlled trial with parallel group design studied the effect of two aerobic exercise-training intensities in COPD patient-centered outcomes. Methods: Thirty-four COPD clinically stable patients stratified from mild to very severe GOLD stages, were blinded to 60 or 80%Wmax aerobic exercise training intensity in an outpatient pulmonary rehabilitation program, between 2009-2010. Outcomes were assessed with St.George's respiratory questionnaire (primary outcome), Mahler dyspnea index, London Chest activity of daily living scale, 6-minute walk, constant load and incremental exercise tests. Patient's allocation sequence was computer-generated, with consignment in a safe deposit box.

Enrollment: 34 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically stable COPD
• FEV1/FVC < 70%
• Exercise training medical referral

Exclusion criteria

• Unable to attend 3-times/week program
• Infectious disease
• Metastatic cancer
• Unstable heart disease
• Neuromusculoskeletal disorder
• Cognitive or psychiatric disorder

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

34 participants in 2 patient groups

60%

Other group

Description:

aerobic exercise training intensity of 60%Wmax

Treatment:

Other: Aerobic exercise training intensity

80%

Other group

Description:

aerobic exercise training intensity of 80%Wmax

Treatment:

Other: Aerobic exercise training intensity