Pulse Oximetry Measurement and Transfusions (POMAT)

Christiana Care Health Services

Status: Completed

Conditions: Premature; Hypoxia Neonatal; Blood Transfusion

Treatments: Other: Transfusion

Study type: Observational

Funder types: Other

Identifiers

NCT04249193

DDD603862

Details and patient eligibility

About

The primary purpose of this observational study was to determine if pRBC transfusions decrease the frequency of intermittent hypoxia events in very low birth weight infants (VLBW) during the first six weeks of life. The impact on non-pRBC transfusions on the frequency of intermittent hypoxia was also assessed.

Enrollment: 75 patients

Sex: All

Ages: Under 6 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 23+0 to 28+6 weeks gestational age at birth

Exclusion criteria

• Infants with life-limiting diagnoses
• Cyanotic heart disease
• In utero fetal transfusion
• Twin to twin transfusion syndrome
• Isoimmune hemolytic disease
• Severe acute hemorrhage
• Acute shock
• Sepsis with coagulopathy
• Need for perioperative transfusion
• Parents opposed to transfusion of blood
• Parents with hemoglobinopathy or congenital anemia

Trial design

75 participants in 1 patient group

Transfusion

Treatment:

Other: Transfusion