Pulse Radiofrequency and Occipital Nerve Block for Chronic Migraine Patients

Aydin Adnan Menderes University

Status: Enrolling

Conditions: Block; Occipital Neuralgia; Chronic Migraine, Headache

Treatments: Procedure: Greater occipital nerve block; Procedure: Greater occipital nerve pulse radiofrequency

Study type: Interventional

Funder types: Other

Identifiers

NCT06247592

2023/03

Details and patient eligibility

About

In this study, the effect of nerve blockade and radiofrequency treatment applied to the nerve on pain in chronic migraine patients will be investigated.

Occipital nerve blockade group (control group): Depending on the location of the pain, blockade will be applied unilaterally or bilaterally with 5 cc of 2% prilocaine for each sıde.

Pulse Radiofrequency application to the greater occipital nerve will be applicated after radiofrequency cannula placed near the greater occipital nerve location with 42 degree, for 240 seconds.

Full description

Patients between the ages of 18-60 years, who were resistant to medical treatment and diagnosed with chronic migraine according to ICHD-3 beta criteria (migraine pain for more than 15 days in the last 3 months) who applied to the Neurology and Algology outpatient clinic were included in the study.

All procedures were performed with the patient in the prone position, using anatomical landmarks in the target areas. For Gon Blockade, the target point for the greater occipital nerve was identified along a line connecting the external occipital protuberance to the mastoid process (usually 1.5-3 cm lateral to the midline) and one-third of the distance medial to the artery at the level of the superior nuchal process. After local anesthesia with skin-subcutaneous 1% lidocaine, bone contact was obtained using a 25-gauge needle. For Pulse Radiofrequency, the target point for the greater occipital nerve was determined as one third of the distance medial to the artery along a line connecting the external occipital protuberance to the mastoid process (usually 1.5-3 cm lateral to the midline) and at the level of the superior nuchal process. After local anesthesia with skin-subcutaneous 1% lidocaine, a 5 cm long 20 gauge radiofrequency needle with a 5 mm active tip was inserted close to the targeted nerve. Sensory and motor electrical stimulation was performed to elicit a compatible paresthesia response in the occipital distribution. Pulsed radiofrequency was applied at 42 degrees C for 240 seconds. Patients were observed after the procedure. Patients were observed before and after the procedure.

Enrollment: 70 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients between 18-60 years of age diagnosed with chronic migraine according to IHS criteria

Exclusion criteria

• Pregnancy
• Major psychiatric disorder
• Bleeding diathesis
• Local infection
• Allergy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

70 participants in 2 patient groups

Radiofrequency group

Experimental group

Description:

Pulse radiofrequency will be applied at 42 degrees for 240 seconds with a channel placed near the greater occipital nerve.

Treatment:

Procedure: Greater occipital nerve pulse radiofrequency

Block group

Active Comparator group

Description:

Nerve blockade will be applied to the greater occipital nerve with 5 cc 2% prilocaine.

Treatment:

Procedure: Greater occipital nerve block