Pulsed Dye Laser Treatment of Onychomycosis

Thomas Jefferson University

Status: Completed

Conditions: Onychomycosis

Treatments: Device: Pulsed Dye Laser for the treatment of nail fungus

Study type: Interventional

Funder types: Other

Identifiers

NCT01915355

IRB 13D.230

Details and patient eligibility

About

The purpose of this research is to investigate the use of the Candela V-beam Pulsed Dye Laser for the treatment of onychomycosis, or nail fungus.

Hypothesis: Complete nail clearance will occur in approximately half of patients after 3 laser treatments.

Full description

10 patients will participate nationally. The investigators hope to enroll all 10 patients at Jefferson. Involvement in the study will last about 8-12 weeks for the subject. The entire study will take about 12 months to complete.

Enrollment: 11 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ages 18-65 years old
• Diagnosis of onychomycosis based on positive fungal culture for dermatophyte and positive PAS from toenail clipping

Exclusion criteria

• HIV/immunosuppression
• Candidal toenail infection
• Prior PO antifungal therapy within last 6 months
• Personal history of psoriasis, lichen planus, or significant photosensitivity disorder
• Any serious generalized medical condition

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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11 participants in 1 patient group

Pulsed Dye Laser for fungus treatment

Experimental group

Description:

The purpose of this research is to investigate the use of the Candela V-beam Pulsed Dye Laser for the treatment of onychomycosis, a common nail fungus.

Treatment:

Device: Pulsed Dye Laser for the treatment of nail fungus