PV Loop & Coarctation Study

University of Minnesota (UMN)

Status: Enrolling

Conditions: Coarctation of Aorta

Treatments: Diagnostic Test: Pressure-volume loop catheter

Study type: Observational

Funder types: Other

Identifiers

NCT05362721

PEDS-2019-27404

Details and patient eligibility

About

Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.

Enrollment: 20 estimated patients

Sex: All

Ages: 6+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children 6 years of age and older and adults of all races and both sexes referred for elective cardiac catheterization and stent therapy for coarctation
• Those who provide informed consent for study participant.

Exclusion criteria

• Children who undergo other interventions in addition to the coarctation
• Children with single ventricle physiology.
• Renal impairment
• Participant unwilling to sign a consent form.

Trial design

20 participants in 1 patient group

Pressure-volume loop catheter

Treatment:

Diagnostic Test: Pressure-volume loop catheter