PVI for TVC Response

National Taiwan University

Status: Unknown

Conditions: Validation of PVI in Tidal Volume Challenge Test

Study type: Observational

Funder types: Other

Identifiers

NCT04978909

202104002RINC

Details and patient eligibility

About

Determine the ability of changes in Plethysmographic Variability Index during tidal volume challenge to predict fluid responsiveness

Full description

The change of Plethysmographic Variability Index after tidal volume challenge as a predictor of fluid responsiveness, confirmed with the change of SVV using Flotrac advance cardiac output monitor.

To determine whether the patient is fluid responder, Fluid challenge will be performed afterwards to confirm the patient's fluid responsiveness.

We also aim to calculate the least significant change for Plethysmographic Variability Index and Philips PPV system.

Enrollment: 50 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion:

Patients undergoing elective major surgery (estimated > 2-hr) with general anesthesia and mechanical ventilation in supine position

Exclusion:

1. BMI < 18.5 or >30 kg/m2
2. Pregnant patient
3. Allergy to starch solution
4. estimated glomerular filtration rate< 60