QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy

Cui Xulei

Status: Completed

Conditions: Nerve Block, Nephrectomy, Analgesia

Treatments: Procedure: preoperative single-shot TPVB; Procedure: preoperative single-shot TMQLB; Drug: patient controlled intravenous analgesia(PCIA)

Study type: Interventional

Funder types: Other

Identifiers

NCT03975296

CXL3

Details and patient eligibility

About

This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and quality of recovery in laparoscopic partial nephrectomy compared with thoracic paravertebral block (TPVB).

Enrollment: 60 patients

Sex: All

Ages: 17 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Age 18-70 yrs American Society of Anesthesiologists physical statusⅠ-Ⅲ Undergo laparoscopic nephrectomy Informed consent

Exclusion criteria

A known allergy to the drugs being used Coagulopathy, on anticoagulants Analgesics intake, history of substance abuse Participating in the investigation of another experimental agent Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

TMQLB group

Experimental group

Treatment:

Drug: patient controlled intravenous analgesia(PCIA)

Procedure: preoperative single-shot TMQLB

TPVB group

Active Comparator group

Treatment:

Procedure: preoperative single-shot TPVB

Drug: patient controlled intravenous analgesia(PCIA)