Quadratus Lumborum Block for Postoperative Analgesia After Colostomy Closure

Sun Yat-sen University logo

Sun Yat-sen University

Status and phase

Unknown
Phase 4

Conditions

Postoperative Pain

Treatments

Drug: normal saline
Drug: levo-bupivacaine

Study type

Interventional

Funder types

Other

Identifiers

NCT02691403
QLCO

Details and patient eligibility

About

Patients undergoing abdominal procedures often require multimodal postoperative pain controls. Truncal blocks such as quadratus lumborum (QL) block may be used adjunctively as a part of it. The investigators hypothesized that the ultrasound-guided QL block with transmuscular approach can provide adequate pain relief for colostomy closure as part of a multimodal pain control.

Enrollment

50 estimated patients

Sex

All

Ages

20 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • A physical status between ASA I and III
  • 20 - 75 years of age
  • Patient has signed an informed consent
  • Without contraindication of QL block

Exclusion Criteria

  • American Society of Anesthesiologists (ASA) Physical Status ≥ 4
  • Any contraindication to nerve blocks (including coagulopathy, abnormal anatomy, infection at the planned QL injection site, and amide-type local anesthetic allergy) pregnancy or breast-feeding
  • Severe obesity (body mass index≥ 35 kg/m2)
  • Patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease
  • Allergy to NSAIDs
  • Infection at the QL injection site
  • Patients with major psychosis or drug and alcohol abuse
  • Patient unable to comprehend or use the verbal rating pain scoring system or patient-controlled analgesia pump

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

50 participants in 2 patient groups

Placebo QL block
Sham Comparator group
Description:
30 ml single shot QL block with saline 0.9%
Treatment:
Drug: normal saline
Active QL block
Active Comparator group
Description:
30 ml single shot QL block with 0.25% levo-bupivacaine
Treatment:
Drug: levo-bupivacaine

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems