Quadratus Lumborum Block Reduced Postpartum Uterine Pain After Virginal Childbirth

Chang Gung Medical Foundation

Status: Completed

Conditions: Quadratus Lumborum Nerve Block; Postpartum Cramping; Vaginal Delivery

Treatments: Procedure: quadratus lumborum nerve block (ropivacaine ); Procedure: quadratus lumborum nerve block (normal saline)

Study type: Interventional

Funder types: Other

Identifiers

NCT05371015

202102060A3

Details and patient eligibility

About

With the continuous advancement of ultrasonic technology, nerve block in which drugs are injected into the periphery of the target nerve through ultrasonic guidance has become the mainstream method for postoperative pain control. The quadratus lumborum nerve block has been effectively and safely used in abdominal surgery (such as laparotomy, caesarean section, etc.), effectively reducing postoperative wounds and visceral pain. There is no research on the use of quadratus lumborum nerve block to control the pain of natural postpartum uterine contractions in the current literature, so the purpose of this experiment is to explore whether the quadratus lumborum nerve block can effectively reduce the pain of uterine contractions after vaginal delivery.

Enrollment: 66 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Females over twenty years of age
• Maternal vaginal delivery
• Postpartum moderate to severe pain with uterine contractions (Numerical Pain Scale (NRS) ≥ 4 points) after delivery.
• Subject's consent signed by the subject

Exclusion criteria

• Severe coagulation abnormalities (PLT<100000、INR>1.2、PT>13)
• Infection of the epidermis at the anticipated relevant site of injection
• Allergy to local anesthetics
• Allergy to or abuse of pain control medications
• Episiotomy is more painful than uterine contractions
• Inability to cooperate with associated pain assessment
• Body Mass Index (BMI) ≧ 35 kg/m2

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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66 participants in 2 patient groups, including a placebo group

quadratus lumborum nerve block group with injection of local anesthetic (Ropivacaine)

Experimental group

Description:

The subjects would have quadratus lumborum nerve block group with injection of local anesthetic (Ropivacaine) after vaginal delivery.

Treatment:

Procedure: quadratus lumborum nerve block (ropivacaine )

quadratus lumborum nerve block with normal saline

Placebo Comparator group

Description:

The subjects would have quadratus lumborum nerve block with normal saline after vaginal delivery.

Treatment:

Procedure: quadratus lumborum nerve block (normal saline)