Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

University of Southern California

Status: Enrolling

Conditions: Lung Non-Small Cell Carcinoma

Treatments: Other: Non-Interventional Study

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT07186699

NCI-2025-05477 (Registry Identifier)

P30CA014089 (U.S. NIH Grant/Contract)

2N-25-7 (Other Identifier)

Details and patient eligibility

About

This study will attempt to identify social facilitators and barriers to detection and treatment of non-small cell lung cancer in order to learn how a history of substance abuse or alcohol use impacts care for non-small cell lung cancer.

Full description

PRIMARY OBJECTIVE:

I. To identify social facilitators and barriers to detection and treatment of NSCLC by interviewing a diverse group of patients at Keck, Los Angeles General Medical Center, and Norris Cancer Center with alcohol or substance use disorder history.

OUTLINE: This is an observational study.

Patients participate in a semi-structured interview and may participate in a follow-up focus group interview in which preliminary findings are shared and feedback is elicited on study.

Enrollment: 45 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• * Adults ≥ 18 years of age

  • Histopathologic or cytologic diagnosis of NSCLC
  • Received or receiving curative intent treatment (e.g. surgery, radiation therapy, systemic therapy)
  • History of alcohol use or substance use disorder (other than tobacco use disorder) within the past 10 years, predating the cancer diagnosis
  • Ability to understand and the willingness to sign a written informed consent
  • English or Spanish speaking. Due to need to conduct semi-structured interviews which can develop into free-flowing conversations we need both participant and interviewer to be fluent

Exclusion criteria

• Patients with cognitive disability unable to maintain 30-60 minute conversation

Trial design

45 participants in 1 patient group

Observational

Description:

Patients participate in a semi-structured interview and may participate in a follow-up focus group interview in which preliminary findings are shared and feedback is elicited on study.

Treatment:

Other: Non-Interventional Study