Quality Control of Pancreatic Islet Intended to Islet Graft Cells Intended to Stabilot Islet Graft Protocol (ISLET CHIP)

Grenoble Alpes University Hospital Center (CHU)

Status: Unknown

Conditions: Pancreatic Islet Quality Control

Study type: Observational

Funder types: Other

Identifiers

NCT03067324

38RC14.041

Details and patient eligibility

About

Islet quality control after pancreatic islets isolation process is insufficient. The Islet Chip study proposes to develop a bio-sensor that will allow a multi-parametric analysis of islet graft based on measurement of islet membrane electric potential.

Full description

Islet quality control after pancreatic islets isolation process is insufficient. The Islet Chip study proposes to develop a bio-sensor that will allow a multi-parametric analysis of islet graft based on measurement of islet membrane electric potential.

The project aims to :

• develop the bio-sensor necessary to measure islet membrane electric potential
• develop interface between bio-sensor and user
• correlate analysis data collected by bio-sensor with metabolic results of islet graft

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients enrolled in STABILOT Pancreatic Islet cell graft protocol and willing to participate to ISLET CHIP

Exclusion criteria

• Patients not enrolled in STABILOT Pancreatic Islet cell graft or patients that signed the form expressing their refuse to participate to ISLET CHIP.