Quality of Life After POEM for Achalasia

Sun Yat-sen University

Status: Unknown

Conditions: Esophageal Achalasia

Treatments: Procedure: Peroral endoscopic myotomy (POEM)

Study type: Observational

Funder types: Other

Identifiers

NCT05010889

124

Details and patient eligibility

About

Achalasia is an esophageal motility disorder, characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Patients with achalasia experience distressing gastrointestinal symptoms, including dysphagia, reflux and chest pain, which lead to weight loss and malnutrition. Undoubtedly, health-related quality of life can be significantly diminished in patients with achalasia. At present, POEM has become one of the standard therapies for achalasia. Limited studies have focused on the patient's quality of life before and after POEM. The present study aimed to assess the changes in quality of life of patients with achalasia using the validated achalasia severity questionnaire (ASQ) and the short form (SF)-36 scale.

Enrollment: 200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed as achalasia base on high resolution manometry, barium esophagram and upper endoscopy
• Scheduled to undergo POEM for treatment of achalasia

Exclusion criteria

• Coagulopathy and systemic disorders that precluded safe general anesthesia

Trial design

200 participants in 1 patient group

Achalasia patients

Description:

Patients schedule to undergo POEM for treatment of symptomatic achalasia. The diagnosis of achalasia was based on high resolution manometry, barium esophagram, and upper endoscopy.

Treatment:

Procedure: Peroral endoscopic myotomy (POEM)