Quality of Life Assessment Between Stroke and Multiple Sclerosis Patients of the Same Age Range (QoLSMS)

Hellenic Red Cross Hospital

Status: Completed

Conditions: Stroke; Mental Health Disorder; Quality of Life; Multiple Sclerosis; Depression

Treatments: Other: Questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT04758494

257/19-12-2019

3320/06-02-2020 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to investigate the physical, psychological, social and functional aspects of life in relatively young people suffering from vascular stroke and in people diagnosed with multiple sclerosis of the same age group and to generally assess the subjective perception of these patients about their general health and well-being. In addition, to assess the degree of depression experienced by people in this age group who suffer from these diseases. Additional objectives are to investigate important factors that negatively affect the quality of life in this group of patients, according to the international literature, and to highlight targeted interventions to promote mental and physical health in order to improve the quality of life in these chronic patients.

Full description

Research on the importance of quality of life in chronic neurological patients has occasionally occupied the international scientific community. Due to the large scale of strokes occurring at young ages as well as multiple sclerosis, more and more research is focusing on the quality of life of these individuals.

The present study is retrospective as well as prospective. The purpose of this study is to investigate the physical, psychological, social and functional aspects of life in relatively young people suffering from vascular stroke and in people diagnosed with multiple sclerosis of the same age group and to generally assess the subjective perception of these patients about their general health and well-being. In addition, to assess the degree of depression experienced by people in this age group who suffer from these diseases. Additional objectives are to investigate important factors that negatively affect the quality of life in this group of patients, according to the international literature, and to highlight targeted interventions to promote mental and physical health in order to improve the quality of life in these chronic patients.

In particular, the research questions that this study is trying to answer are:

• Do young stroke patients exhibit the same quality of life as healthy populations of the same age?
• Do young people with multiple sclerosis have the same quality of life as the healthy population of the same age?
• Do young people with stroke have the same quality of life as patients with multiple sclerosis of the same age?
• Are patients (either with multiple sclerosis or stroke) with almost the same degree of physical independence and are older patients characterized by greater depression and reduced quality of life compared to younger ones?
• Is degree of disability associated with decreased quality of life and increased depression between the two groups of chronic patients?
• Does gender affect the quality of life and the presence of depression?
• Do marital and economic status affect the indicators of depression and quality of life in both populations to be investigated?
• Is location of living a factor that contributes to the reduced quality of life and the triggering of depression in young people with stroke and multiple sclerosis compared to the healthy population?

Enrollment: 172 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Greek citizenship
• Age 18-60 years
• Hospitalization at the department of Neurology, G. Gennimatas Hospital or at the department of Vascular Surgery and/or Neurosurgery, Hellenic Red Cross Hospital
• Diagnosis of ischemic or hemorrhagic stroke or multiple sclerosis at discharge from hospital

Exclusion criteria

• Alien citizenship
• Age below 18 or above 60 years
• Mental or physical disability history before the diagnosis of stroke or multiple sclerosis
• Second stroke during the period of the study
• History of dementia
• Symptoms of aphasia or individuals in comatose state (high NIHS)
• Individuals with stroke in the frontal lobe

Trial design

172 participants in 6 patient groups

Stroke1-hemiparesis

Description:

Patients diagnosed with an ischemic/hemorrhagic stroke and clinical hemiparesis.

Treatment:

Other: Questionnaire

Stroke 2-mild stroke

Description:

Patients diagnosed with an ischemic/hemorrhagic stroke and clinical symptoms of a mild stroke.

Treatment:

Other: Questionnaire

Stroke 3-speech disorder

Description:

Patients diagnosed with an ischemic/hemorrhagic stroke and clinical symptoms of a speech disorder.

Treatment:

Other: Questionnaire

Stroke 4-hemiparesis mainly of upper limb

Description:

Patients diagnosed with an ischemic/hemorrhagic stroke and clinical hemiparesis mainly of upper limb.

Treatment:

Other: Questionnaire

Stroke 5-memory loss and depression

Description:

Patients diagnosed with an ischemic/hemorrhagic stroke and clinical symptoms of memory loss and depression.

Treatment:

Other: Questionnaire

Multiple Sclerosis

Description:

Patients diagnosed with multiple sclerosis.

Treatment:

Other: Questionnaire