Quality of Life in Advanced Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy

Peking University Cancer Hospital & Institute

Status

Unknown

Conditions

QOL; Quality of Life;Gastric Cancer; Gastrectomy;Neoadjuvant Chemotherapy

Treatments

Drug: Neoadjuvant Chemotherapy

Study type

Observational

Funder types

Other

Identifiers

NCT04408859

QOL-201804

Details and patient eligibility

About

The purpose of this study is to explore the influence of neoadjuvant chemotherapy in the long term quality of life with advanced gastric cancer patients.

Full description

Preoperative adjuvant chemotherapy combined with postoperative adjuvant therapy mode was included in the 2018 version of the National Comprehensive Cancer Network (NCCN) guideline as an optional treatment (category 2B) for prospective resectable advanced gastric cancer cases (≥cT2, any N).At home and abroad, the research on neoadjuvant chemotherapy for advanced gastric cancer mainly focuses on the safety and long-term survival, and there are few studies on the quality of life. This study, according to EORTC QLQ-C30 and QLQ-STO22 assessment scale, explores the long term effect of neoadjuvant chemotherapy on the quality of life in patients with advanced gastric cancer.

Enrollment

290 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients age older than 18 years (including 18 years old);
Diagnosis of adenocarcinoma of the stomach
The clinic stage is ≥T2 and any N stage
Patient had curative surgical resection, including proximal, distal, or total gastrectomy

Exclusion criteria

Psychiatric or psychological abnormality precluding informed consent or ability to complete questionnaires
Non-psychiatric disorder causing a lack of capacity to give consent or an inability to complete questionnaires (ie dementia, stroke)
Early gastric cancer.