Quality of Life in Presbyopes Using Single-vision Lens and Progressive Lens Correction

The Hong Kong Polytechnic University

Status: Not yet enrolling

Conditions: Presbyopia Correction; Presbyopia

Treatments: Behavioral: Progressive lenses intervention; Behavioral: Single-vision lenses intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT06699784

HSEARS20240916011

Details and patient eligibility

About

The goal of this clinical trial is to compare the quality of life (QOL) of presbyopes wearing progressive addition lenses (PALs) with that of those wearing single-vision spectacles (SVSs) for near correction. The main questions it aims to answer is:

What is the difference in QOL between presbyopes who use SVSs and those who use PALs ? Eligible participants will be randomly assigned in a 1:1 ratio to either the PALs group or the SVSs group.Participants in the progressive lenses intervention group will receive 1-month progressive lens correction in daily life. And participants in single-vision lenses intervention group will use near-vision spectacles during near work and use their original habitual distant glasses for distance tasks for 1 month.

The study will compare the QOL scores measured by a 12-item Near Vision-Related Quality of Life questionnaire between the two groups. Additionally, the study will compare the scores measured by the Refractive Status and Vision Profile questionnaire and Visual Analogue Scale questionnaire between the two groups as well as assess the change in the above three questionnaires scores at 1 month following enrollment. And visual acuity of subjects will also be assessed at baseline and at the 1-month follow-up.

Enrollment: 74 estimated patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 40-70 years;
2. A distant correction of ≤2D for hyperopia, or >-2 D for myopia, or < 2D for astigmatism in both eyes;
3. Anisometropia of less than 1.50 D;
4. Distance best-corrected visual acuity (BCVA) of at least 0.5 LogMAR, and near VA < N8 (20/50) at 40 cm with habitually worn distance refractive correction, with improvement of near vision by at least one line on a near LogMAR E chart with the use of a plus lens;
5. Have not undergone any near correction in the past six months;
6. Able to answer a questionnaire;
7. Giving written consent to participate in the study.

Exclusion criteria

1. Ocular abnormalities leading to visual impairment including severe cataract, glaucoma, strabismus, and ocular fundus diseases;
2. Severe physiological and psychological diseases affecting follow-up;
3. History of cataract surgery, phakic intraocular lens surgery, corneal surgery, or any intraocular surgery affecting the refractive status of the eye;
4. Have used pilocarpine in the past six months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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74 participants in 2 patient groups, including a placebo group

Progressive lenses intervention group

Experimental group

Description:

Progressive lenses intervention group will receive 1-month progressive lens correction in daily life.

Treatment:

Behavioral: Progressive lenses intervention

Single-vision lenses intervention group

Placebo Comparator group

Description:

Single-vision lenses intervention group will use near-vision spectacles during near work and use their original habitual distant glasses for distance tasks for 1 month.

Treatment:

Behavioral: Single-vision lenses intervention