Quality of Pediatric Resuscitation in a Multicenter Collaborative (pediRES-Q)

Children's Hospital of Philadelphia (CHOP)

Status: Enrolling

Conditions: Cardiopulmonary Arrest; Cardiac Arrest

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02708134

15-012099

Details and patient eligibility

About

This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests.

The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.

Full description

Cardiac arrests in children are a major public health problem. Thousands of children each year in the USA are treated with cardiopulmonary resuscitation (CPR) and managed after their cardiac arrest. Neurological outcomes following these in-hospital CPR events are often abnormal. As children with neurological deficits following CPR are a major burden for families and society, improving neurological outcomes through superior chest compression delivery during CPR and optimal care and management after cardiac arrest is an important clinical goal.

Therefore, the objective of this investigation is to obtain evidentiary support to associate the relationship of quantitative CPR quality data (depth, rate, chest compressions (CC) fraction, compression release) during CPR, post-cardiac arrest care (PCAC) and patient survival in those children who suffer an arrest within the study (RES-Q) Network.

Enrollment: 7,000 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient received chest compressions for at least 1 minute
• Patient between gestational age ≥37 weeks and 18 years of age

Exclusion criteria

• Patient on veno-arterial extracorporeal membrane oxygenation (ECMO) therapy at beginning of CPR event

Trial design

7,000 participants in 1 patient group

Pediatric Cardiac Arrests

Description:

Pediatric cardiac arrests requiring chest compressions for at least 1 minute managed at clinical centers identified as part of standard clinical operations.