Quality of Recovery of Remimazolam Versus Sevoflurane in Transurethral Bladder Resection.

Kangbuk Samsung Hospital

Status: Completed

Conditions: Quality of Recovery

Treatments: Drug: Sevoflurane; Drug: Remimazolam

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05356091

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Details and patient eligibility

About

This study was designated to investigate the quality of recovery after transurethral bladder resection. Because, patients undergoing transurethral bladder resection are mostly old age, and because of catheter-related bladder discomfort are common after transurethral bladder resection, study on the quality of recovery after transurethral bladder resection seems to be meaningful. In general, sevoflurane is commonly used as an anesthetic agent for general anesthesia of transurethral bladder resection. The purpose of this study is to investigate whether remimazolam is not inferior to sevoflurnane in terms of quality of recovery after transurethral bladder resection.

Enrollment: 36 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients aged from 19 years
• Americaln Society of Anesthesiologist's class I, II, and III
• scheduled to undergo elective transurethral bladder resection under general anesthesia

Exclusion criteria

• refuse to participate in the study
• cannot read, or sign the consent form (e.g., iliterate, foreigner, eye disease)
• history of allergy to benzodiazepines
• decreased liver, kidney, or heart function
• pregnant women or breastfeeding patients
• history of drug or alcohol abuse
• obesity (body mass index > 30kg/m2)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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36 participants in 2 patient groups

Sevoflurane

Active Comparator group

Description:

General anesthesia using sevoflurane

Treatment:

Drug: Sevoflurane

Remimazolam

Experimental group

Description:

General anesthesia using remimazolam

Treatment:

Drug: Remimazolam