Quantification of Cannabinoids and Comparison to Post-Surgical Pain Medication Requirements and Surgical Outcomes

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Cannabis Use; Post-Surgical Pain; Cancer; Post-Surgical Complication

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04988490

NCI-2021-08865 (Other Identifier)

21-3544.cc

P30CA046934 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

To determine how daily cannabis use affects surgical outcomes.

Full description

To determine if patients who are daily cannabis users that are undergoing inpatient abdominal surgery for the treatment of cancer are different from non-cannabis users regarding phytocannabinoid and endocannabinoid levels, pain scores, pain medication requirements, and surgical complications.

Enrollment: 68 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients > 18 years old
• Undergoing abdominal surgery for the treatment of cancer
• Report no cannabis use in the last year or chronic cannabis use (defined as at least weekly use for 3 months or more)

Exclusion criteria

• patients with chronic pain, chronic pain syndrome on opioids
• female patients who are pregnant or lactating
• patients who report use of illicit substances

Trial design

68 participants in 2 patient groups

Daily cannabis users

Description:

Patients undergoing inpatient abdominal surgery for the treatment of cancer who self-report daily cannabis use

Cannabis non-users

Description:

Patients undergoing inpatient abdominal surgery for the treatment of cancer who self-report no cannabis use