Quantification of Internal Training Load (QUADRATURE)

Université de Nantes

Status: Not yet enrolling

Conditions: Muscle; Resistance Training; Hypertrophy

Treatments: Other: strength training

Study type: Interventional

Funder types: Other

Identifiers

NCT06164249

EM_LL_2024

Details and patient eligibility

About

The aim of this study is to determine whether the distribution of internal load predicts the distribution of muscle hypertrophy among hamstring heads after a 10-week resistance exercise program. The hypothesis is that the distribution of internal muscle load among the hamstring is related to the distribution of muscle hypertrophy.

Full description

It is well accepted that muscle stress (mechanical and/or metabolic) is the major way to induce muscle hypertrophy. While this link between muscle stress and hypertrophy is pivotal is sport training, prevention and rehabilitation, it remains poorly understood. To date, the only indirect evidence of relationship of muscle stress and muscle hypertrophy is the similar patterns (from independent studies) between muscle damage and hypertrophy within quadriceps (i.e., rectus femoris (RF) > vastus (VL) = vastus medialis VM), hamstring, and triceps surae. However, muscle damage is an indirect proof of muscle mechanical stress. With the quantification of internal muscle load, it is interesting to determine whether the muscle that receives the larger stress exhibits the larger hypertrophy.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No history of lower limb injury
• No chronic pathology associated with a long term care

Exclusion criteria

• Individual enrolled in a research study

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 3 patient groups

Nordic

Experimental group

Description:

Training regimens composed of nordic exercise

Treatment:

Other: strength training

Deadlift

Experimental group

Description:

Training regimens composed of deadlift exercise

Treatment:

Other: strength training

Control

No Intervention group

Description:

Training regimens composed of no exercise