ClinicalTrials.Veeva

Menu

Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser

A

Alexandria University

Status and phase

Completed
Phase 3
Phase 2

Conditions

Periodontal Pocket

Treatments

Device: medency diode laser
Drug: spirazole forte

Study type

Interventional

Funder types

Other

Identifiers

NCT05222737
lasers in periodontology

Details and patient eligibility

About

  1. Primary objective To measure the gingival crevicular levels of A.actinomycetemcomitans and P.gingivalis after intra-pocket application of diode laser in severe periodontitis (stage 3 grade C) patients.
  2. Secondary objective To compare the levels of the same microorganisms as in cases of diode laser therapy to those after conventional treatment with systemic antibiotic administration in severe periodontitis (stage 3 grade C) patients.
  3. to measure clinical parameters probing depth,attachment loss and mobility grade

Enrollment

50 patients

Sex

All

Ages

15 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. Patients of both sexes having severe periodontitis (stage 3 grade C) with interdental clinical attachment loss (CAL) ≥ 5.
  2. Patients' age between 15 and 35 years old with rapid bone loss showed by radiograph.
  3. Systemically healthy patients.
  4. Radiographic bone loss extending to middle or apical third of root.
  5. Probing depth (PD) ≥ 6 mm.

Exclusion criteria

  1. Use of antibiotics during the last 3 months.
  2. Pregnancy.
  3. Any systemic condition that might affect the study.
  4. Use of mouthwash containing antimicrobials during the previous 3 weeks.
  5. Smoking.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

50 participants in 2 patient groups

test group
Active Comparator group
Description:
intra pocket diode laser application
Treatment:
Device: medency diode laser
control group
Active Comparator group
Description:
antibiotic adminstration
Treatment:
Drug: spirazole forte

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems