Quantitative EEG Markers in Mild Cognitive Impairment in Epilepsy

Mansoura University Hospital

Status

Completed

Conditions

Epilepsy

Treatments

Device: Electroencephalography

Study type

Observational

Funder types

Other

Identifiers

NCT04376671

Mansoura University 15

Details and patient eligibility

About

Epileptic patients are plighted with limited daily activities, social dysfunction, family conflicts and cognitive impairment. Most of the studies had showed that cognitive disorders were frequent in patients with epilepsy.The cognitive impairment has been reported in around 25% of epileptic patients.

Full description

Cognitive consequences in epilepsy are often described in the following domains: verbal memory, language, executive functions, and attention. However, most of the studies focus on one or two domains in a relatively small sample.

Few studies have investigated the influential factors for the epilepsy-related cognitive impairment . However, most of these studies merely focused on one or a few potential factors and failed to consider possible distractions from other influential factors. Therefore, it is crucial to include more potential factors in the analysis and to rule out possible confounding interactions between factors.

Enrollment

90 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with clinically confirmed epilepsy in adult patients.
Non-symptomatic epilepsy.
Normal CT or MRI brain, and
Education level of primary school at least to respond to the scales correctly were included.

Exclusion criteria

Psycho-neurological illnesses,
History of alcoholism or drug abuse, or
Recently on medications that may affect cognitive functions (like antidepressants and antipsychotic drugs).