Quantitative Renal Uptake Using TC99m DMSA in Hypertensive &/or Diabetic Patients.

Assiut University

Status and phase: Unknown; Phase 4

Conditions: Hypertension; Diabetes Mellitus

Treatments: Diagnostic Test: DMSA scan

Study type: Interventional

Funder types: Other

Identifiers

NCT03123237

DMSA

Details and patient eligibility

About

the investigators explore the possible role of DMSA to detect renal affection in diabetic &/or hypertensive patients by detecting difference in counts using Tc 99m DMSA in control & diabetic &/or hypertensive patients.

Enrollment: 45 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Patients with diabetes (type2), weather controlled or not.

  • Patients with essential hypertension.
  • Patients with diabetes & hypertension.
  • Within normal renal function (urea & creatinine).
  • Control cases may be normal individuals (apparently healthy) like donors for renal transplant.

Exclusion criteria

• • Patients with abnormal renal function.

  • Patients with diseases known to affect kidney function rather diabetes & hypertension e.g. SLE, heart failure or liver cell failure.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 4 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

control will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Treatment:

Diagnostic Test: DMSA scan

Diabetic

Active Comparator group

Description:

diabetic cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Treatment:

Diagnostic Test: DMSA scan

Hypertensive

Active Comparator group

Description:

hypertesive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Treatment:

Diagnostic Test: DMSA scan

Diabetic & Hypertensive

Active Comparator group

Description:

Diabetic \& Hypertensive cases will be subjected to: • Quantitative Tc99m DMSA renal scan using SPECT technique.

Treatment:

Diagnostic Test: DMSA scan