Quantitative Sensory Testing in Subjects With Sensitive Skin or Not (SENSISKIN)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Sensitive Skin

Treatments: Device: Quantitative Sensory Testing

Study type: Interventional

Funder types: Other

Identifiers

NCT03081403

SENSISKIN 29CRB16.0100

Details and patient eligibility

About

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Full description

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Enrollment: 42 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: between 20 and 60 years
• Cooperating patient
• Informed and written consent of the subject
• Affiliated to the social security
• For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

• To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion criteria

• Adults subject with legal protection
• Subject in a social institution.
• Subject with major cognitive or psychiatric disorders
• Subject with pathological use of alcohol or consumption of another drug.
• Subject with skin involvement of the back of the dominant hand or malformation.
• Known sensitive neuropathy
• Pregnant woman
• Subject receiving medical treatment which may interfere with the results.
• Subject with treatment in the back of the dominant hand.

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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42 participants in 2 patient groups

Subjects with sensitive skin

Other group

Description:

Subjects with a score greater than 50 on the sensitive scale

Treatment:

Device: Quantitative Sensory Testing

Subjects without sensitive skin

Other group

Description:

Subjects with result lower than 20 on the sensitive scale

Treatment:

Device: Quantitative Sensory Testing