Quantitative Studies of Urinary Bladder Sensation

Timothy Ness, MD

Status

Completed

Conditions

Interstitial Cystitis

Treatments

Other: Quantitative Sensory Testing and Stimulus

Study type

Observational

Funder types

Other

NIH

Identifiers

NCT00903435

F060505003

3R01DK051413-11S1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems.

Full description

To determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems. Previous studies by the PI suggest that two populations of subjects are present in the IC population but a larger number of subjects with IC would need to be tested in order to determine if this were indeed true. Other studies have demonstrated that counterirritation-related effects are absent in several chronic pain populations including fibromyalgia and chronic headaches. Identification of a subset of IC patients or the identification of a failure of counterirritation-related effects may predict responses to therapeutic interventions.

Enrollment

60 patients

Sex

All

Ages

19 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria